Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project

C. A. Stiller; S. S. Bielack; G. Jundt; E. Steliarova-Foucher; S. V. Petrovich; O. Budanov; H. Storm; N. Christensen; T. Aareleid; T. Hakulinen; R. Sankila; E. Pukkala; E. Le Gall; I. Tron; B. Lacour; E. Desandes; J. L. Bernard; P. Pillon; J. C. Gentet; F. Freycon; C. Berger; L. Remontet; A. Danzon; M. Mercier; J. P. Daurès; B. Tretarre; F. Ménégoz; A. V. Guizard; M. Velten; A. Buemi; N. Raverdy; M. Sauvage; P. Grosclaude; P. Kaatsch; B. Eisinger; R. Stabenow; D. Schuler; Z. Jakab; G. Borgulya; L. Tryggvadottir; J. G. Jonasson; K. Bjarnadottir; H. Comber; F. Dwane; C. Magnani; G. Pastore; F. Pannelli; C. Pascucci; S. Ferretti; E. Conti; V. Ramazzotti; M. C. Cercato; M. Vercelli; A. Puppo; P. Crosignani; G. Tagliabue; A. Tittarelli; V. De Lisi; P. Sgargi; R. Zanetti; S. Patriarca; R. Tumino; M. Budroni; D. Piras; E. Paci; E. Crocetti; F. La Rosa; F. Stracci; P. Zambon; S. Guzzinati; M. Dalmas; J. W.W. Coebergh; J. van Dijck; A. Wit; F. Langmark; A. Johansen; A. Andersen; I. Plesko; M. Primic Z? akelj; V. Pompe-Kirn; R. Peris-Bonet; B. Giner; E. Almar Marques; A. Mateos Ramos; J. Ramon Quiros Garcia; A. Can ada Martínez; I. Izarzugaza; A. Alemán Herrera; P. Viladiu; R. Marcos; A. Izquierdo; C. Martínez Garcia; A. Obrador; I. Garau; E. Ardanaz; J. Borràs; J. Galceran; J. de la Bárcena Guallar; M. C. Martos Jiménez; C. Bouchardy; M. Usel; J. Allemann; H. Frick; T. Fisch; S. Ess; F. Joris; D. de Weck; S. Yalcin Eser; M. F.G. Murphy; G. J. Draper; A. Gavin; C. Fox; W. Hamill; R. Middleton; D. Brewster; L. Bhatti; A. McDonald

doi:10.1016/j.ejca.2006.05.015

Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project

C. A. Stiller, S. S. Bielack, G. Jundt, E. Steliarova-Foucher, S. V. Petrovich, O. Budanov, H. Storm, N. Christensen, T. Aareleid, T. Hakulinen, R. Sankila, E. Pukkala, E. Le Gall, I. Tron, B. Lacour, E. Desandes, J. L. Bernard, P. Pillon, J. C. Gentet, F. FreyconC. Berger, L. Remontet, A. Danzon, M. Mercier, J. P. Daurès, B. Tretarre, F. Ménégoz, A. V. Guizard, M. Velten, A. Buemi, N. Raverdy, M. Sauvage, P. Grosclaude, P. Kaatsch, B. Eisinger, R. Stabenow, D. Schuler, Z. Jakab, G. Borgulya, L. Tryggvadottir, J. G. Jonasson, K. Bjarnadottir, H. Comber, F. Dwane, C. Magnani, G. Pastore, F. Pannelli, C. Pascucci, S. Ferretti, E. Conti, V. Ramazzotti, M. C. Cercato, M. Vercelli, A. Puppo, P. Crosignani, G. Tagliabue, A. Tittarelli, V. De Lisi, P. Sgargi, R. Zanetti, S. Patriarca, R. Tumino, M. Budroni, D. Piras, E. Paci, E. Crocetti, F. La Rosa, F. Stracci, P. Zambon, S. Guzzinati, M. Dalmas, J. W.W. Coebergh, J. van Dijck, A. Wit, F. Langmark, A. Johansen, A. Andersen, I. Plesko, M. Primic Z? akelj, V. Pompe-Kirn, R. Peris-Bonet, B. Giner, E. Almar Marques, A. Mateos Ramos, J. Ramon Quiros Garcia, A. Can ada Martínez, I. Izarzugaza, A. Alemán Herrera, P. Viladiu, R. Marcos, A. Izquierdo, C. Martínez Garcia, A. Obrador, I. Garau, E. Ardanaz, J. Borràs, J. Galceran, J. de la Bárcena Guallar, M. C. Martos Jiménez, C. Bouchardy, M. Usel, J. Allemann, H. Frick, T. Fisch, S. Ess, F. Joris, D. de Weck, S. Yalcin Eser, M. F.G. Murphy, G. J. Draper, A. Gavin, C. Fox, W. Hamill, R. Middleton, D. Brewster, L. Bhatti, A. McDonald

Research output: Contribution to journal › Article › peer-review

Abstract

Data on 5572 children and adolescents diagnosed with malignant bone tumours (International Classification of Childhood Cancer, Group VIII) before the age of 20 years during 1978-1997 in Europe were extracted from the Automated Childhood Cancer Information System (ACCIS) database. Age-standardised incidence among children during the period 1988-1997 was similar for boys and girls aged 0-14 years (5.5-5.6 per million). Among adolescents aged 15-19 years, males had higher incidence (19.3 per million) than females (10.7 per million). Among children, osteosarcoma accounted for 51% of registrations and Ewing's sarcoma for 41%. Among adolescents, 55% of registrations were osteosarcoma and 28% Ewing's sarcoma. Both tumours had their highest incidence in late childhood or early adolescence. There were no significant time trends in incidence during 1978-1997. Five-year survival estimates for patients diagnosed during 1988-1997 were, respectively, 59% and 51% among children and adolescents with osteosarcoma and 62% and 30% among children and adolescents with Ewing's sarcoma. Between 1978-1982 and 1993-1997, survival increased for both children and adolescents with osteosarcoma, and for children with Ewing's sarcoma.

Original language	English
Pages (from-to)	2124-2135
Number of pages	12
Journal	European Journal of Cancer
Volume	42
Issue number	13
DOIs	https://doi.org/10.1016/j.ejca.2006.05.015
Publication status	Published - 1 Sept 2006

Bibliographical note

Funding Information: The ACCIS project was funded by the European Commission from the ’Europe Against Cancer’ programme (1996–2002, contracts SI2.126875, SI2.321970 and SPC.2002303), jointly with the International Agency for Research on Cancer (IARC). Data analyses were partly funded by the French Ligue Nationale contre le Cancer, Comité du Rhône. The Childhood Cancer Research Group receives funding from the Department of Health and the Scottish Ministers. The views expressed in the publication are those of the authors and not necessarily those of the Department of Health and the Scottish Ministers.

Other keywords

Adolescent
Bone neoplasms
Childhood cancer
Epidemiology
Europe
Ewing's sarcoma
Incidence
Osteosarcoma
Registry
Survival

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10.1016/j.ejca.2006.05.015

Cite this

Stiller, C. A., Bielack, S. S., Jundt, G., Steliarova-Foucher, E., Petrovich, S. V., Budanov, O., Storm, H., Christensen, N., Aareleid, T., Hakulinen, T., Sankila, R., Pukkala, E., Le Gall, E., Tron, I., Lacour, B., Desandes, E., Bernard, J. L., Pillon, P., Gentet, J. C., ... McDonald, A. (2006). Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project. European Journal of Cancer, 42(13), 2124-2135. https://doi.org/10.1016/j.ejca.2006.05.015

@article{a41abfe74aa340679ebd442de072a56c,

title = "Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project",

abstract = "Data on 5572 children and adolescents diagnosed with malignant bone tumours (International Classification of Childhood Cancer, Group VIII) before the age of 20 years during 1978-1997 in Europe were extracted from the Automated Childhood Cancer Information System (ACCIS) database. Age-standardised incidence among children during the period 1988-1997 was similar for boys and girls aged 0-14 years (5.5-5.6 per million). Among adolescents aged 15-19 years, males had higher incidence (19.3 per million) than females (10.7 per million). Among children, osteosarcoma accounted for 51\% of registrations and Ewing's sarcoma for 41\%. Among adolescents, 55\% of registrations were osteosarcoma and 28\% Ewing's sarcoma. Both tumours had their highest incidence in late childhood or early adolescence. There were no significant time trends in incidence during 1978-1997. Five-year survival estimates for patients diagnosed during 1988-1997 were, respectively, 59\% and 51\% among children and adolescents with osteosarcoma and 62\% and 30\% among children and adolescents with Ewing's sarcoma. Between 1978-1982 and 1993-1997, survival increased for both children and adolescents with osteosarcoma, and for children with Ewing's sarcoma.",

keywords = "Adolescent, Bone neoplasms, Childhood cancer, Epidemiology, Europe, Ewing's sarcoma, Incidence, Osteosarcoma, Registry, Survival",

author = "Stiller, \{C. A.\} and Bielack, \{S. S.\} and G. Jundt and E. Steliarova-Foucher and Petrovich, \{S. V.\} and O. Budanov and H. Storm and N. Christensen and T. Aareleid and T. Hakulinen and R. Sankila and E. Pukkala and \{Le Gall\}, E. and I. Tron and B. Lacour and E. Desandes and Bernard, \{J. L.\} and P. Pillon and Gentet, \{J. C.\} and F. Freycon and C. Berger and L. Remontet and A. Danzon and M. Mercier and Daur{\`e}s, \{J. P.\} and B. Tretarre and F. M{\'e}n{\'e}goz and Guizard, \{A. V.\} and M. Velten and A. Buemi and N. Raverdy and M. Sauvage and P. Grosclaude and P. Kaatsch and B. Eisinger and R. Stabenow and D. Schuler and Z. Jakab and G. Borgulya and L. Tryggvadottir and Jonasson, \{J. G.\} and K. Bjarnadottir and H. Comber and F. Dwane and C. Magnani and G. Pastore and F. Pannelli and C. Pascucci and S. Ferretti and E. Conti and V. Ramazzotti and Cercato, \{M. C.\} and M. Vercelli and A. Puppo and P. Crosignani and G. Tagliabue and A. Tittarelli and \{De Lisi\}, V. and P. Sgargi and R. Zanetti and S. Patriarca and R. Tumino and M. Budroni and D. Piras and E. Paci and E. Crocetti and \{La Rosa\}, F. and F. Stracci and P. Zambon and S. Guzzinati and M. Dalmas and Coebergh, \{J. W.W.\} and \{van Dijck\}, J. and A. Wit and F. Langmark and A. Johansen and A. Andersen and I. Plesko and \{Primic Z? akelj\}, M. and V. Pompe-Kirn and R. Peris-Bonet and B. Giner and \{Almar Marques\}, E. and \{Mateos Ramos\}, A. and \{Ramon Quiros Garcia\}, J. and \{Can ada Mart{\'i}nez\}, A. and I. Izarzugaza and \{Alem{\'a}n Herrera\}, A. and P. Viladiu and R. Marcos and A. Izquierdo and \{Mart{\'i}nez Garcia\}, C. and A. Obrador and I. Garau and E. Ardanaz and J. Borr{\`a}s and J. Galceran and \{de la B{\'a}rcena Guallar\}, J. and \{Martos Jim{\'e}nez\}, \{M. C.\} and C. Bouchardy and M. Usel and J. Allemann and H. Frick and T. Fisch and S. Ess and F. Joris and \{de Weck\}, D. and \{Yalcin Eser\}, S. and Murphy, \{M. F.G.\} and Draper, \{G. J.\} and A. Gavin and C. Fox and W. Hamill and R. Middleton and D. Brewster and L. Bhatti and A. McDonald",

note = "Funding Information: The ACCIS project was funded by the European Commission from the {\textquoteright}Europe Against Cancer{\textquoteright} programme (1996–2002, contracts SI2.126875, SI2.321970 and SPC.2002303), jointly with the International Agency for Research on Cancer (IARC). Data analyses were partly funded by the French Ligue Nationale contre le Cancer, Comit{\'e} du Rh{\^o}ne. The Childhood Cancer Research Group receives funding from the Department of Health and the Scottish Ministers. The views expressed in the publication are those of the authors and not necessarily those of the Department of Health and the Scottish Ministers.",

year = "2006",

month = sep,

day = "1",

doi = "10.1016/j.ejca.2006.05.015",

language = "English",

volume = "42",

pages = "2124--2135",

journal = "European Journal of Cancer",

issn = "0959-8049",

publisher = "Elsevier Ltd.",

number = "13",

}

Stiller, CA, Bielack, SS, Jundt, G, Steliarova-Foucher, E, Petrovich, SV, Budanov, O, Storm, H, Christensen, N, Aareleid, T, Hakulinen, T, Sankila, R, Pukkala, E, Le Gall, E, Tron, I, Lacour, B, Desandes, E, Bernard, JL, Pillon, P, Gentet, JC, Freycon, F, Berger, C, Remontet, L, Danzon, A, Mercier, M, Daurès, JP, Tretarre, B, Ménégoz, F, Guizard, AV, Velten, M, Buemi, A, Raverdy, N, Sauvage, M, Grosclaude, P, Kaatsch, P, Eisinger, B, Stabenow, R, Schuler, D, Jakab, Z, Borgulya, G, Tryggvadottir, L, Jonasson, JG, Bjarnadottir, K, Comber, H, Dwane, F, Magnani, C, Pastore, G, Pannelli, F, Pascucci, C, Ferretti, S, Conti, E, Ramazzotti, V, Cercato, MC, Vercelli, M, Puppo, A, Crosignani, P, Tagliabue, G, Tittarelli, A, De Lisi, V, Sgargi, P, Zanetti, R, Patriarca, S, Tumino, R, Budroni, M, Piras, D, Paci, E, Crocetti, E, La Rosa, F, Stracci, F, Zambon, P, Guzzinati, S, Dalmas, M, Coebergh, JWW, van Dijck, J, Wit, A, Langmark, F, Johansen, A, Andersen, A, Plesko, I, Primic Z? akelj, M, Pompe-Kirn, V, Peris-Bonet, R, Giner, B, Almar Marques, E, Mateos Ramos, A, Ramon Quiros Garcia, J, Can ada Martínez, A, Izarzugaza, I, Alemán Herrera, A, Viladiu, P, Marcos, R, Izquierdo, A, Martínez Garcia, C, Obrador, A, Garau, I, Ardanaz, E, Borràs, J, Galceran, J, de la Bárcena Guallar, J, Martos Jiménez, MC, Bouchardy, C, Usel, M, Allemann, J, Frick, H, Fisch, T, Ess, S, Joris, F, de Weck, D, Yalcin Eser, S, Murphy, MFG, Draper, GJ, Gavin, A, Fox, C, Hamill, W, Middleton, R, Brewster, D, Bhatti, L & McDonald, A 2006, 'Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project', European Journal of Cancer, vol. 42, no. 13, pp. 2124-2135. https://doi.org/10.1016/j.ejca.2006.05.015

TY - JOUR

T1 - Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project

AU - Stiller, C. A.

AU - Bielack, S. S.

AU - Jundt, G.

AU - Steliarova-Foucher, E.

AU - Petrovich, S. V.

AU - Budanov, O.

AU - Storm, H.

AU - Christensen, N.

AU - Aareleid, T.

AU - Hakulinen, T.

AU - Sankila, R.

AU - Pukkala, E.

AU - Le Gall, E.

AU - Tron, I.

AU - Lacour, B.

AU - Desandes, E.

AU - Bernard, J. L.

AU - Pillon, P.

AU - Gentet, J. C.

AU - Freycon, F.

AU - Berger, C.

AU - Remontet, L.

AU - Danzon, A.

AU - Mercier, M.

AU - Daurès, J. P.

AU - Tretarre, B.

AU - Ménégoz, F.

AU - Guizard, A. V.

AU - Velten, M.

AU - Buemi, A.

AU - Raverdy, N.

AU - Sauvage, M.

AU - Grosclaude, P.

AU - Kaatsch, P.

AU - Eisinger, B.

AU - Stabenow, R.

AU - Schuler, D.

AU - Jakab, Z.

AU - Borgulya, G.

AU - Tryggvadottir, L.

AU - Jonasson, J. G.

AU - Bjarnadottir, K.

AU - Comber, H.

AU - Dwane, F.

AU - Magnani, C.

AU - Pastore, G.

AU - Pannelli, F.

AU - Pascucci, C.

AU - Ferretti, S.

AU - Conti, E.

AU - Ramazzotti, V.

AU - Cercato, M. C.

AU - Vercelli, M.

AU - Puppo, A.

AU - Crosignani, P.

AU - Tagliabue, G.

AU - Tittarelli, A.

AU - De Lisi, V.

AU - Sgargi, P.

AU - Zanetti, R.

AU - Patriarca, S.

AU - Tumino, R.

AU - Budroni, M.

AU - Piras, D.

AU - Paci, E.

AU - Crocetti, E.

AU - La Rosa, F.

AU - Stracci, F.

AU - Zambon, P.

AU - Guzzinati, S.

AU - Dalmas, M.

AU - Coebergh, J. W.W.

AU - van Dijck, J.

AU - Wit, A.

AU - Langmark, F.

AU - Johansen, A.

AU - Andersen, A.

AU - Plesko, I.

AU - Primic Z? akelj, M.

AU - Pompe-Kirn, V.

AU - Peris-Bonet, R.

AU - Giner, B.

AU - Almar Marques, E.

AU - Mateos Ramos, A.

AU - Ramon Quiros Garcia, J.

AU - Can ada Martínez, A.

AU - Izarzugaza, I.

AU - Alemán Herrera, A.

AU - Viladiu, P.

AU - Marcos, R.

AU - Izquierdo, A.

AU - Martínez Garcia, C.

AU - Obrador, A.

AU - Garau, I.

AU - Ardanaz, E.

AU - Borràs, J.

AU - Galceran, J.

AU - de la Bárcena Guallar, J.

AU - Martos Jiménez, M. C.

AU - Bouchardy, C.

AU - Usel, M.

AU - Allemann, J.

AU - Frick, H.

AU - Fisch, T.

AU - Ess, S.

AU - Joris, F.

AU - de Weck, D.

AU - Yalcin Eser, S.

AU - Murphy, M. F.G.

AU - Draper, G. J.

AU - Gavin, A.

AU - Fox, C.

AU - Hamill, W.

AU - Middleton, R.

AU - Brewster, D.

AU - Bhatti, L.

AU - McDonald, A.

N1 - Funding Information: The ACCIS project was funded by the European Commission from the ’Europe Against Cancer’ programme (1996–2002, contracts SI2.126875, SI2.321970 and SPC.2002303), jointly with the International Agency for Research on Cancer (IARC). Data analyses were partly funded by the French Ligue Nationale contre le Cancer, Comité du Rhône. The Childhood Cancer Research Group receives funding from the Department of Health and the Scottish Ministers. The views expressed in the publication are those of the authors and not necessarily those of the Department of Health and the Scottish Ministers.

PY - 2006/9/1

Y1 - 2006/9/1

N2 - Data on 5572 children and adolescents diagnosed with malignant bone tumours (International Classification of Childhood Cancer, Group VIII) before the age of 20 years during 1978-1997 in Europe were extracted from the Automated Childhood Cancer Information System (ACCIS) database. Age-standardised incidence among children during the period 1988-1997 was similar for boys and girls aged 0-14 years (5.5-5.6 per million). Among adolescents aged 15-19 years, males had higher incidence (19.3 per million) than females (10.7 per million). Among children, osteosarcoma accounted for 51% of registrations and Ewing's sarcoma for 41%. Among adolescents, 55% of registrations were osteosarcoma and 28% Ewing's sarcoma. Both tumours had their highest incidence in late childhood or early adolescence. There were no significant time trends in incidence during 1978-1997. Five-year survival estimates for patients diagnosed during 1988-1997 were, respectively, 59% and 51% among children and adolescents with osteosarcoma and 62% and 30% among children and adolescents with Ewing's sarcoma. Between 1978-1982 and 1993-1997, survival increased for both children and adolescents with osteosarcoma, and for children with Ewing's sarcoma.

AB - Data on 5572 children and adolescents diagnosed with malignant bone tumours (International Classification of Childhood Cancer, Group VIII) before the age of 20 years during 1978-1997 in Europe were extracted from the Automated Childhood Cancer Information System (ACCIS) database. Age-standardised incidence among children during the period 1988-1997 was similar for boys and girls aged 0-14 years (5.5-5.6 per million). Among adolescents aged 15-19 years, males had higher incidence (19.3 per million) than females (10.7 per million). Among children, osteosarcoma accounted for 51% of registrations and Ewing's sarcoma for 41%. Among adolescents, 55% of registrations were osteosarcoma and 28% Ewing's sarcoma. Both tumours had their highest incidence in late childhood or early adolescence. There were no significant time trends in incidence during 1978-1997. Five-year survival estimates for patients diagnosed during 1988-1997 were, respectively, 59% and 51% among children and adolescents with osteosarcoma and 62% and 30% among children and adolescents with Ewing's sarcoma. Between 1978-1982 and 1993-1997, survival increased for both children and adolescents with osteosarcoma, and for children with Ewing's sarcoma.

KW - Adolescent

KW - Bone neoplasms

KW - Childhood cancer

KW - Epidemiology

KW - Europe

KW - Ewing's sarcoma

KW - Incidence

KW - Osteosarcoma

KW - Registry

KW - Survival

UR - http://www.scopus.com/inward/record.url?scp=33747358308&partnerID=8YFLogxK

U2 - 10.1016/j.ejca.2006.05.015

DO - 10.1016/j.ejca.2006.05.015

M3 - Article

C2 - 16919776

SN - 0959-8049

VL - 42

SP - 2124

EP - 2135

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 13

ER -

Bone tumours in European children and adolescents, 1978-1997. Report from the Automated Childhood Cancer Information System project

Abstract

Bibliographical note

Other keywords

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