Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene

C. Szpirer; J. Szpirer; M. Riviere; S. Ingvarsson; B. Vennstrom; M. Q.G. Islam Levan

Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene

C. Szpirer
, J. Szpirer
, M. Riviere
, S. Ingvarsson
, B. Vennstrom
, M. Q.G. Islam Levan

Faculty of Medicine

University of Iceland

Research output: Contribution to journal › Article › peer-review

Abstract

Using a panel of somatic cell hybrids that segregate rat chromosomes, the localization of five cancer-related rat genes was determined: (i) two thyroid receptor genes, THRA1/ERBA1 and THRB/ERBA2 on chromosomes 10 and 15 respectively, (ii) two ERBB genes, namely the epidermal growth factor gene (EGFR, also called ERBB1) and the ERBB2 gene (also designated neu) on chromosomes 14 and 10 respectively, and (iii) the retinoblastoma gene, RB1, on chromosome 15. The THRA1/ERBA1 and ERBB2/neu genes are thus included in a synteny group, conserved on rat chromosomes 10 and human chromosome arm 17q.

Original language	English
Pages (from-to)	1319-1324
Number of pages	6
Journal	Oncogene
Volume	6
Issue number	8
Publication status	Published - 1991

Cite this

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title = "Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene",

abstract = "Using a panel of somatic cell hybrids that segregate rat chromosomes, the localization of five cancer-related rat genes was determined: (i) two thyroid receptor genes, THRA1/ERBA1 and THRB/ERBA2 on chromosomes 10 and 15 respectively, (ii) two ERBB genes, namely the epidermal growth factor gene (EGFR, also called ERBB1) and the ERBB2 gene (also designated neu) on chromosomes 14 and 10 respectively, and (iii) the retinoblastoma gene, RB1, on chromosome 15. The THRA1/ERBA1 and ERBB2/neu genes are thus included in a synteny group, conserved on rat chromosomes 10 and human chromosome arm 17q.",

author = "C. Szpirer and J. Szpirer and M. Riviere and S. Ingvarsson and B. Vennstrom and \{Islam Levan\}, \{M. Q.G.\}",

year = "1991",

language = "English",

volume = "6",

pages = "1319--1324",

journal = "Oncogene",

issn = "0950-9232",

publisher = "Springer Nature",

number = "8",

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TY - JOUR

T1 - Chromosomal assignment of five cancer-associated rat genes

T2 - Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene

AU - Szpirer, C.

AU - Szpirer, J.

AU - Riviere, M.

AU - Ingvarsson, S.

AU - Vennstrom, B.

AU - Islam Levan, M. Q.G.

PY - 1991

Y1 - 1991

N2 - Using a panel of somatic cell hybrids that segregate rat chromosomes, the localization of five cancer-related rat genes was determined: (i) two thyroid receptor genes, THRA1/ERBA1 and THRB/ERBA2 on chromosomes 10 and 15 respectively, (ii) two ERBB genes, namely the epidermal growth factor gene (EGFR, also called ERBB1) and the ERBB2 gene (also designated neu) on chromosomes 14 and 10 respectively, and (iii) the retinoblastoma gene, RB1, on chromosome 15. The THRA1/ERBA1 and ERBB2/neu genes are thus included in a synteny group, conserved on rat chromosomes 10 and human chromosome arm 17q.

AB - Using a panel of somatic cell hybrids that segregate rat chromosomes, the localization of five cancer-related rat genes was determined: (i) two thyroid receptor genes, THRA1/ERBA1 and THRB/ERBA2 on chromosomes 10 and 15 respectively, (ii) two ERBB genes, namely the epidermal growth factor gene (EGFR, also called ERBB1) and the ERBB2 gene (also designated neu) on chromosomes 14 and 10 respectively, and (iii) the retinoblastoma gene, RB1, on chromosome 15. The THRA1/ERBA1 and ERBB2/neu genes are thus included in a synteny group, conserved on rat chromosomes 10 and human chromosome arm 17q.

UR - https://www.scopus.com/pages/publications/0025740940

M3 - Article

C2 - 1679528

SN - 0950-9232

VL - 6

SP - 1319

EP - 1324

JO - Oncogene

JF - Oncogene

IS - 8

ER -

Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene

Abstract

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