Complete genome sequence of Streptomyces lividans TK24

Christian Rückert; Andreas Albersmeier; Tobias Busche; Sebastian Jaenicke; Anika Winkler; Ólafur H. Fridjónsson; Gudmundur Óli Hreggvidsson; Christophe Lambert; Daniel Badcock; Kristel Bernaerts; Jozef Anne; Anastassios Economou; Jörn Kalinowski

doi:10.1016/j.jbiotec.2015.02.004

Complete genome sequence of Streptomyces lividans TK24

Christian Rückert, Andreas Albersmeier, Tobias Busche, Sebastian Jaenicke, Anika Winkler, Ólafur H. Fridjónsson, Gudmundur Óli Hreggvidsson, Christophe Lambert, Daniel Badcock, Kristel Bernaerts, Jozef Anne, Anastassios Economou, Jörn Kalinowski

Faculty of Life and Environmental Sciences

University of Iceland

Research output: Contribution to journal › Article › peer-review

Abstract

Streptomyces lividans TK24 is the standard host for the heterologous expression of a number of different proteins and antibiotic-synthesizing enzymes. As such, it is often used as an experimental microbial cell factory for the production of secreted heterologous proteins including human cytokines and industrial enzymes, and of several antibiotics. It accepts methylated DNA and is an ideal Streptomyces cloning system. Here, we report the complete genome sequence of S. lividans TK24 that includes a plasmid-less genome of 8.345. Mbp (72.24% G. +. C content).

Original language	English
Pages (from-to)	21-22
Number of pages	2
Journal	Journal of Biotechnology
Volume	199
DOIs	https://doi.org/10.1016/j.jbiotec.2015.02.004
Publication status	Published - 1 Apr 2015

Bibliographical note

Funding Information: We are grateful to: colleagues of the Streptomics and StrepSynth networks for useful discussions. Progenus is acknowledged for the earlier S. lividans sequence reads obtained by Ion Torrent technology. The project was funded by the EU : FP6 project Streptomics, LSHG-CT-2007-037586 (to OF, CL, DB, JA and AE) and FP7 project StrepSynth, n°613877 (to OF, KB, JA, AE, and JK). Publisher Copyright: © 2015 Elsevier B.V.

Other keywords

Genome sequence
Heterologous protein expression
Model organism
Streptomyces

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10.1016/j.jbiotec.2015.02.004

Cite this

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title = "Complete genome sequence of Streptomyces lividans TK24",

abstract = "Streptomyces lividans TK24 is the standard host for the heterologous expression of a number of different proteins and antibiotic-synthesizing enzymes. As such, it is often used as an experimental microbial cell factory for the production of secreted heterologous proteins including human cytokines and industrial enzymes, and of several antibiotics. It accepts methylated DNA and is an ideal Streptomyces cloning system. Here, we report the complete genome sequence of S. lividans TK24 that includes a plasmid-less genome of 8.345. Mbp (72.24\% G. +. C content).",

keywords = "Genome sequence, Heterologous protein expression, Model organism, Streptomyces",

author = "Christian R{\"u}ckert and Andreas Albersmeier and Tobias Busche and Sebastian Jaenicke and Anika Winkler and Fridj{\'o}nsson, \{{\'O}lafur H.\} and Hreggvidsson, \{Gudmundur {\'O}li\} and Christophe Lambert and Daniel Badcock and Kristel Bernaerts and Jozef Anne and Anastassios Economou and J{\"o}rn Kalinowski",

note = "Funding Information: We are grateful to: colleagues of the Streptomics and StrepSynth networks for useful discussions. Progenus is acknowledged for the earlier S. lividans sequence reads obtained by Ion Torrent technology. The project was funded by the EU : FP6 project Streptomics, LSHG-CT-2007-037586 (to OF, CL, DB, JA and AE) and FP7 project StrepSynth, n°613877 (to OF, KB, JA, AE, and JK). Publisher Copyright: {\textcopyright} 2015 Elsevier B.V.",

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doi = "10.1016/j.jbiotec.2015.02.004",

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AU - Rückert, Christian

AU - Albersmeier, Andreas

AU - Busche, Tobias

AU - Jaenicke, Sebastian

AU - Winkler, Anika

AU - Fridjónsson, Ólafur H.

AU - Hreggvidsson, Gudmundur Óli

AU - Lambert, Christophe

AU - Badcock, Daniel

AU - Bernaerts, Kristel

AU - Anne, Jozef

AU - Economou, Anastassios

AU - Kalinowski, Jörn

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KW - Genome sequence

KW - Heterologous protein expression

KW - Model organism

KW - Streptomyces

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SP - 21

EP - 22

JO - Journal of Biotechnology

JF - Journal of Biotechnology

ER -

Complete genome sequence of Streptomyces lividans TK24

Abstract

Bibliographical note

Other keywords

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Cite this