Expa: A program for calculating extreme pathways in biochemical reaction networks

Steven L. Bell; Bernhard Palsson

doi:10.1093/bioinformatics/bti228

Expa: A program for calculating extreme pathways in biochemical reaction networks

Steven L. Bell
, Bernhard Palsson

University of Iceland

University of Iceland

Research output: Contribution to journal › Article › peer-review

Abstract

Summary: The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software.

Original language	English
Pages (from-to)	1739-1740
Number of pages	2
Journal	Bioinformatics
Volume	21
Issue number	8
DOIs	https://doi.org/10.1093/bioinformatics/bti228
Publication status	Published - 15 Apr 2005

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title = "Expa: A program for calculating extreme pathways in biochemical reaction networks",

abstract = "Summary: The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software.",

author = "Bell, \{Steven L.\} and Bernhard Palsson",

note = "Funding Information: Financial support for this work was provided by a grant from the National Institutes of Health (GM68837). Bernhard Palsson serves on the Scientific Advisory board of Genomatica.",

year = "2005",

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AU - Palsson, Bernhard

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PY - 2005/4/15

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N2 - Summary: The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software.

AB - Summary: The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software.

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DO - 10.1093/bioinformatics/bti228

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JO - Bioinformatics

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Expa: A program for calculating extreme pathways in biochemical reaction networks

Abstract

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