Abstract
Loading and release characteristics of insulin-carrying albumin and starch microspheres have been studied in vitro. The sorption characteristics of 125I-labelled insulin onto albumin microspheres were studied and were found to be completed within 5h, and the loading capacity was found to be 0.14% w/w. Insulin did not show any sorption into the matrix of the starch microspheres. The release characteristics were analyzed by high performance liquid chromatography. About 80% was released within 5-10 min from albumin microspheres and starch microspheres, respectively.
| Original language | English |
|---|---|
| Pages (from-to) | 1892-1893 |
| Number of pages | 2 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 39 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1991 |
Other keywords
- adsorption
- insulin
- microsphere
- release
- sorption