Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant: A Case Report

Einar A Helgason; Þórunn Óskarsdóttir; Hrólfur Brynjarsson; Ingvar Hákon Ólafsson; Valtýr Stefánsson Thors

doi:10.1097/inf.0000000000003403

Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant: A Case Report

Einar A Helgason, Þórunn Óskarsdóttir, Hrólfur Brynjarsson, Ingvar Hákon Ólafsson, Valtýr Stefánsson Thors

University of Iceland, Landspitali

Research output: Contribution to journal › Article › peer-review

Abstract

Posthemorragic hydrocephalus is a relatively common condition in prematures, often requiring ventriculoperitoneal shunts. We report a case of methicillin-resistant Staphylococcus aureus infection of a ventriculoperitoneal shunt in a premature neonate which failed conventional intravenous treatment. Despite the absence of published guidelines, we used available data and expert advice to treat the patient with intraventricular vancomycin. The treatment was successful in eradicating the infection without observed toxicity. This case highlights the need for international guidelines on intraventricular treatment for neonates.

Original language	English
Pages (from-to)	340-342
Number of pages	3
Journal	The Pediatric infectious disease journal
Volume	41
Issue number	4
DOIs	https://doi.org/10.1097/inf.0000000000003403
Publication status	Published - 1 Apr 2022

Bibliographical note

Other keywords

Anti-Bacterial Agents/therapeutic use
Cerebral Ventriculitis/drug therapy
Encephalitis/drug therapy
Humans
Hydrocephalus/drug therapy
Infant
Infant, Newborn
Infant, Premature
Methicillin-Resistant Staphylococcus aureus
Myelitis
Vancomycin/therapeutic use
Ventriculoperitoneal Shunt/adverse effects
prematurity
ventriculitis vancomycin
ventriculoperitoneal shunt

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10.1097/inf.0000000000003403

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title = "Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant: A Case Report",

abstract = "Posthemorragic hydrocephalus is a relatively common condition in prematures, often requiring ventriculoperitoneal shunts. We report a case of methicillin-resistant Staphylococcus aureus infection of a ventriculoperitoneal shunt in a premature neonate which failed conventional intravenous treatment. Despite the absence of published guidelines, we used available data and expert advice to treat the patient with intraventricular vancomycin. The treatment was successful in eradicating the infection without observed toxicity. This case highlights the need for international guidelines on intraventricular treatment for neonates.",

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author = "Helgason, \{Einar A\} and {\TH}{\'o}runn {\'O}skarsd{\'o}ttir and Hr{\'o}lfur Brynjarsson and {\'O}lafsson, \{Ingvar H{\'a}kon\} and Thors, \{Valt{\'y}r Stef{\'a}nsson\}",

year = "2022",

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doi = "10.1097/inf.0000000000003403",

language = "English",

volume = "41",

pages = "340--342",

journal = "The Pediatric infectious disease journal",

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Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant: A Case Report. / Helgason, Einar A; Óskarsdóttir, Þórunn ; Brynjarsson, Hrólfur et al.
In: The Pediatric infectious disease journal, Vol. 41, No. 4, 01.04.2022, p. 340-342.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant

T2 - A Case Report

AU - Helgason, Einar A

AU - Óskarsdóttir, Þórunn

AU - Brynjarsson, Hrólfur

AU - Ólafsson, Ingvar Hákon

AU - Thors, Valtýr Stefánsson

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KW - Encephalitis/drug therapy

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KW - Hydrocephalus/drug therapy

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KW - Infant, Newborn

KW - Infant, Premature

KW - Methicillin-Resistant Staphylococcus aureus

KW - Myelitis

KW - Vancomycin/therapeutic use

KW - Ventriculoperitoneal Shunt/adverse effects

KW - prematurity

KW - ventriculitis vancomycin

KW - ventriculoperitoneal shunt

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DO - 10.1097/inf.0000000000003403

M3 - Article

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SN - 1532-0987

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SP - 340

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JO - The Pediatric infectious disease journal

JF - The Pediatric infectious disease journal

IS - 4

ER -

Intraventricular Vancomycin Treatment for Shunt-related Ventriculitis Caused by Methicillin-resistant Staphylococcus Aureus in a Preterm Infant: A Case Report

Abstract

Bibliographical note

Other keywords

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