@article{fe193b53dc434087b51fdc9c9faf886f,
title = "MS og barnsbur{\dh}ur: Sj{\'u}kd{\'o}msvirkni og {\'u}tkoma me{\dh}g{\"o}ngu og f{\ae}{\dh}ingar",
abstract = "INNGANGUR MS (multiple sclerosis) er langvinnur b{\'o}lgusj{\'u}kd{\'o}mur {\'i} mi{\dh}taugakerfi sem einkennist af k{\"o}stum, einkum hj{\'a} ungu f{\'o}lki, konum frekar en k{\"o}rlum. Me{\dh}g{\"o}ngu- og f{\ae}{\dh}ingarsaga {\'i}slenskra kvenna me{\dh} MS hefur ekki veri{\dh} ranns{\"o}ku{\dh} {\'a}{\dh}ur. Markmi{\dh} ranns{\'o}knarinnar var tv{\'i}{\th}{\ae}tt, annars vegar a{\dh} sko{\dh}a sj{\'u}kd{\'o}msmynd MS {\'a} me{\dh}g{\"o}ngu og fyrstu m{\'a}nu{\dh}um eftir f{\ae}{\dh}ingu og hins vegar a{\dh} kanna {\'u}tkomu me{\dh}g{\"o}ngu og f{\ae}{\dh}ingar kvenna me{\dh} MS og bera saman vi{\dh} h{\'o}p kvenna sem ekki hafa greinst me{\dh} MS e{\dh}a annan langvinnan sj{\'u}kd{\'o}m. EFNIVI{\DH}UR OG A{\DH}FER{\DH}IR Afturskyggn ranns{\'o}kn {\'a} g{\"o}gnum {\'u}r sj{\'u}kraskr{\'a} Landsp{\'i}tala og F{\ae}{\dh}ingaskr{\'a}ningu Emb{\ae}ttis landl{\ae}knis sem n{\'a}{\dh}i til kvenna me{\dh} greininguna MS (ICD-10: G35) {\'a} {\'a}runum 2009-2018 og f{\ae}{\dh}inga {\th}eirra {\'a} t{\'i}mabilinu 1999-2018, alls 91 konu og 137 f{\ae}{\dh}inga. NI{\DH}URST{\"O}{\DH}UR K{\"o}stum f{\ae}kka{\dh}i {\'a} fyrsta og {\"o}{\dh}rum {\th}ri{\dh}jungi me{\dh}g{\"o}ngu mi{\dh}a{\dh} vi{\dh} {\'a}ri{\dh} fyrir {\th}ungun. R{\'u}mlega helmingur kvennanna var {\'a} fyrirbyggjandi lyfjame{\dh}fer{\dh} fyrir me{\dh}g{\"o}ngu og h{\ae}ttu {\th}{\ae}r allar me{\dh}fer{\dh}inni um e{\dh}a fyrir getna{\dh}. Konur me{\dh} MS f{\ae}ddu oftar me{\dh} keisaraskur{\dh}i {\'a}n f{\ae}{\dh}ingars{\'o}ttar. Me{\dh}g{\"o}ngulengd kvenna me{\dh} MS var samb{\ae}rileg vi{\dh} samanbur{\dh}arh{\'o}p {\th}egar s{\'o}tt h{\'o}fst sj{\'a}lfkrafa. Ekki var munur {\'a} fj{\"o}lda l{\'e}ttbura e{\dh}a {\th}ungbura milli h{\'o}pa. Apgar-stigun var samb{\ae}rileg milli h{\'o}pa. {\'A}LYKTUN Vi{\dh} teljum a{\dh} ranns{\'o}kn okkar endurspegli vel me{\dh}g{\"o}ngu- og f{\ae}{\dh}ingars{\"o}gu kvenna me{\dh} MS {\'a} {\'I}slandi og a{\dh} ni{\dh}urst{\"o}{\dh}ur s{\'y}ni a{\dh} {\th}{\ae}r skeri sig l{\'i}tt {\'u}r almennu {\th}{\'y}{\dh}i. Ni{\dh}urst{\"o}{\dh}ur okkar samr{\'y}mast erlendum ranns{\'o}knum um l{\ae}gri kastat{\'i}{\dh}ni {\'a} me{\dh}g{\"o}ngu en munurinn er {\th}{\'o} s{\'a} a{\dh} {\'i} okkar ranns{\'o}kn eru {\th}au {\'a}hrif bundin vi{\dh} fyrsta og annan {\th}ri{\dh}jung me{\dh}g{\"o}ngu. Introduction: Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system which affects young people, especially women. The aim of the study was to examine the disease profile of MS during pregnancy and postpartum as well as pregnancy outcomes in women with MS compared to a control group. Such a study has not been conducted in Iceland before. Material and methods: A hospital based retrospective study with data from the Icelandic Medical Birth Register and medical records from Landspitali University Hospital including women with MS diagnosis during 2009-2018 and their deliveries through 1999-2018, a total of 91 women and 137 births. Results: Relapse frequency decreased during pregnancy compared to the preceding year. Over half of the women received disease modifying drugs before pregnancy, all stopped treatment before or shortly after conception. Women in the study group underwent cesarean sections before labor more frequently than the control group. The gestational length was comparable between the groups when labor was spontaneous. The numbers of heavy- and lightweight newborns as well as Apgar scores were alike in both groups. Conclusion: We believe that our study reflects actual pregnancy outcome among Icelandic women with MS and our results show that their pregnancies and deliveries do not differ in any major aspect from the general population. Our findings agree with previous studies in that pregnancy protects against MS relapses although in our study this is confined to the first and second trimester.",
keywords = "Breastfeeding, Multiple sclerosis, Pregnancy and delivery outcome, Relapse frequency",
author = "Berg{\th}{\'o}rsd{\'o}ttir, \{Brynd{\'i}s Bj{\"o}rk\} and P{\'o}rhallsd{\'o}ttir, \{Rebekka L{\'i}sa\} and {\TH}{\'o}ra Steingr{\'i}msd{\'o}ttir and Haukur Hjaltason and {\TH}{\'o}rhallsd{\'o}ttir, \{Rebekka L{\'i}sa\}",
note = "Publisher Copyright: {\textcopyright} 2020 Laeknafelag Islands. All rights reserved.",
year = "2020",
doi = "10.17992/LBL.2020.12.612",
language = "{\'I}slenska",
volume = "106",
pages = "281--289",
journal = "Laeknabladid",
issn = "0023-7213",
publisher = "Icelandic Medical Association",
number = "12",
}