Retinal oxygenation and laser treatment in patients with diabetic retinopathy

E. Stefansson, R. Machemer, E. De Juan, B. W. McCuen, J. Peterson

Research output: Contribution to journalArticlepeer-review

Abstract

The oxygen tension in the preretinal vitreous cavity was measured in human patients undergoing vitreous operations for proliferative diabetic retinopathy. The oxygen tension was significantly higher (P = .004) over areas of retina that had been treated with panretinal photocoagulation than it was over untreated areas in the same retina. This confirmed previous results in animals that showed that panretinal photocoagulation increases the inner retinal oxygen tension. We concluded that panretinal photocoagulation improves the oxygen supply to the inner retina and thereby minimizes the influence of retinal ischemia in diabetic retinopathy.

Original languageEnglish
Pages (from-to)36-38
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume113
Issue number1
DOIs
Publication statusPublished - 1992

Bibliographical note

Funding Information: From the Department of Ophthalmology, University of Iceland, Landakotsspitali, Reykjavik, Iceland (Dr. Stefansson); Duke University Eye Center, Durham, North Carolina (Drs. Machemer, de Juan, and McCuen); and National Institutes of Health, Bethesda, Maryland (Dr. Peterson). This study was presented in part at the annual meeting of the Association for Research in Vision and Ophthalmology in Sarasota, Florida on May 2, 1990. This study was supported by National Institutes of Health grant RO1-7001 (Dr. Stefansson), the Icelandic Science Foundation, Reykjavik, Iceland (Dr. Stefansson), and Landakotsspitali Foundation, Reykjavik, Iceland (Dr. Stefansson).

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