Robust deformable image registration using prior shape information for atlas to patient registration

Lotta M. Ellingsen, Gouthami Chintalapani, Russell H. Taylor, Jerry L. Prince

Research output: Contribution to journalArticlepeer-review

Abstract

Statistical atlases enable the individualization of atlas information for patient specific applications such as surgical planning. In this paper, a statistical atlas comprising a point distribution model defined on the vertices of a tetrahedral mesh is registered to a subject's computed tomography scan of the human pelvis. The approach consists of a volumetric deformable registration method augmented to maintain the topology of the atlas mesh after deformation as well as incorporating the dominant three-dimensional shape modes in the atlas. Experimental results demonstrate that incorporation of the statistical shape atlas helps to stabilize the registration and improves robustness and registration accuracy.

Original languageEnglish
Pages (from-to)79-90
Number of pages12
JournalComputerized Medical Imaging and Graphics
Volume34
Issue number1
DOIs
Publication statusPublished - Jan 2010

Bibliographical note

Funding Information: This work was supported by NIH/NIBIB grant 5R21EB003616 and NSF EEC9731478. The authors would like to thank Ms. Pauline Pelletier for her assistance on manual processing of data.

Other keywords

  • Computed tomography-CT
  • Deformable image registration
  • Pelvis
  • Point distribution model
  • Principal component analysis-PCA
  • Prior shape information
  • Statistical atlas
  • Surgical planning
  • Tetrahedral mesh
  • Topology

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