Syntheses, spectral aspects and biological studies of bromide and azide bridged box dimer copper(II) complexes of an NNO donor aroylhydrazone

M. M. Fousiamol; M. Sithambaresan; Krishna K. Damodaran; M. R.Prathapachandra Kurup

doi:10.1016/j.ica.2019.119301

Syntheses, spectral aspects and biological studies of bromide and azide bridged box dimer copper(II) complexes of an NNO donor aroylhydrazone

M. M. Fousiamol
, M. Sithambaresan
, Krishna K. Damodaran
, M. R.Prathapachandra Kurup

Faculty of Physical Sciences

University of Iceland

Research output: Contribution to journal › Article › peer-review

Abstract

A new NNO donor aroylhydrazone, di-2-pyridyl ketone-3-methoxybenzhydrazone (Hdkm) and three copper(II) complexes of Hdkm have been synthesized and characterized by different physicochemical techniques including single crystal X-ray diffraction technique. The structural analysis of copper(II) complexes revealed that a mononuclear bis coordinated complex [Cu(dkm)₂] (1) and two monocoordinated Hdkm with dinuclear metal center [Cu(dkm)Br]₂ (2) and [Cu(dkm)N₃]₂ (3) are formed. The coordination geometry of complex 1 is distorted octahedral with an N₄O₂ chromophore while complexes 2 and 3 are bromide and azide bridged box dimers respectively with distorted square pyramidal geometry. These complexes showed a axial spectra with g_|| > g_⊥ ≥ 2.0023. The antibacterial activity and cytotoxicity studies performed showed that these complexes display good activity.

Original language	English
Article number	119301
Journal	Inorganica Chimica Acta
Volume	501
DOIs	https://doi.org/10.1016/j.ica.2019.119301
Publication status	Published - 1 Feb 2020

Bibliographical note

Funding Information: M. M. Fousiamol is thankful to the Cochin University of Science and Technology, Kochi, India (Ac.1/Ph.D/2013-14 dated 18-10-2013) and DST-PURSE (SP/751(PURSE-II)/2016) for financial assistance. The authors are thankful to Erasmus + for support. The authors are thankful to the Sophisticated Analytical Instrumentation Facility (SAIF), Kochi India for elemental analyses, NMR spectra and single crystal X-ray diffraction measurements. We also thank the IIT Bombay, India for EPR measurements. Funding Information: M. M. Fousiamol is thankful to the Cochin University of Science and Technology, Kochi, India (Ac.1/Ph.D/2013-14 dated 18-10-2013) and DST-PURSE (SP/751(PURSE-II)/2016) for financial assistance. The authors are thankful to Erasmus + for support. The authors are thankful to the Sophisticated Analytical Instrumentation Facility (SAIF), Kochi India for elemental analyses, NMR spectra and single crystal X-ray diffraction measurements. We also thank the IIT Bombay, India for EPR measurements. Appendix A Publisher Copyright: © 2019 Elsevier B.V.

Other keywords

Axial spectra
Box dimer
Copper(II) complex
Distorted square pyramidal
Methoxybenzhydrazone
NO chromophore

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10.1016/j.ica.2019.119301

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@article{4436b76596f64652b87e06eb698e5d2a,

title = "Syntheses, spectral aspects and biological studies of bromide and azide bridged box dimer copper(II) complexes of an NNO donor aroylhydrazone",

abstract = "A new NNO donor aroylhydrazone, di-2-pyridyl ketone-3-methoxybenzhydrazone (Hdkm) and three copper(II) complexes of Hdkm have been synthesized and characterized by different physicochemical techniques including single crystal X-ray diffraction technique. The structural analysis of copper(II) complexes revealed that a mononuclear bis coordinated complex [Cu(dkm)2] (1) and two monocoordinated Hdkm with dinuclear metal center [Cu(dkm)Br]2 (2) and [Cu(dkm)N3]2 (3) are formed. The coordination geometry of complex 1 is distorted octahedral with an N4O2 chromophore while complexes 2 and 3 are bromide and azide bridged box dimers respectively with distorted square pyramidal geometry. These complexes showed a axial spectra with g|| > g⊥ ≥ 2.0023. The antibacterial activity and cytotoxicity studies performed showed that these complexes display good activity.",

keywords = "Axial spectra, Box dimer, Copper(II) complex, Distorted square pyramidal, Methoxybenzhydrazone, NO chromophore",

author = "Fousiamol, \{M. M.\} and M. Sithambaresan and Damodaran, \{Krishna K.\} and Kurup, \{M. R.Prathapachandra\}",

note = "Funding Information: M. M. Fousiamol is thankful to the Cochin University of Science and Technology, Kochi, India (Ac.1/Ph.D/2013-14 dated 18-10-2013) and DST-PURSE (SP/751(PURSE-II)/2016) for financial assistance. The authors are thankful to Erasmus + for support. The authors are thankful to the Sophisticated Analytical Instrumentation Facility (SAIF), Kochi India for elemental analyses, NMR spectra and single crystal X-ray diffraction measurements. We also thank the IIT Bombay, India for EPR measurements. Funding Information: M. M. Fousiamol is thankful to the Cochin University of Science and Technology, Kochi, India (Ac.1/Ph.D/2013-14 dated 18-10-2013) and DST-PURSE (SP/751(PURSE-II)/2016) for financial assistance. The authors are thankful to Erasmus + for support. The authors are thankful to the Sophisticated Analytical Instrumentation Facility (SAIF), Kochi India for elemental analyses, NMR spectra and single crystal X-ray diffraction measurements. We also thank the IIT Bombay, India for EPR measurements. Appendix A Publisher Copyright: {\textcopyright} 2019 Elsevier B.V.",

year = "2020",

month = feb,

day = "1",

doi = "10.1016/j.ica.2019.119301",

language = "English",

volume = "501",

journal = "Inorganica Chimica Acta",

issn = "0020-1693",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Syntheses, spectral aspects and biological studies of bromide and azide bridged box dimer copper(II) complexes of an NNO donor aroylhydrazone

AU - Fousiamol, M. M.

AU - Sithambaresan, M.

AU - Damodaran, Krishna K.

AU - Kurup, M. R.Prathapachandra

N1 - Funding Information: M. M. Fousiamol is thankful to the Cochin University of Science and Technology, Kochi, India (Ac.1/Ph.D/2013-14 dated 18-10-2013) and DST-PURSE (SP/751(PURSE-II)/2016) for financial assistance. The authors are thankful to Erasmus + for support. The authors are thankful to the Sophisticated Analytical Instrumentation Facility (SAIF), Kochi India for elemental analyses, NMR spectra and single crystal X-ray diffraction measurements. We also thank the IIT Bombay, India for EPR measurements. Funding Information: M. M. Fousiamol is thankful to the Cochin University of Science and Technology, Kochi, India (Ac.1/Ph.D/2013-14 dated 18-10-2013) and DST-PURSE (SP/751(PURSE-II)/2016) for financial assistance. The authors are thankful to Erasmus + for support. The authors are thankful to the Sophisticated Analytical Instrumentation Facility (SAIF), Kochi India for elemental analyses, NMR spectra and single crystal X-ray diffraction measurements. We also thank the IIT Bombay, India for EPR measurements. Appendix A Publisher Copyright: © 2019 Elsevier B.V.

PY - 2020/2/1

Y1 - 2020/2/1

N2 - A new NNO donor aroylhydrazone, di-2-pyridyl ketone-3-methoxybenzhydrazone (Hdkm) and three copper(II) complexes of Hdkm have been synthesized and characterized by different physicochemical techniques including single crystal X-ray diffraction technique. The structural analysis of copper(II) complexes revealed that a mononuclear bis coordinated complex [Cu(dkm)2] (1) and two monocoordinated Hdkm with dinuclear metal center [Cu(dkm)Br]2 (2) and [Cu(dkm)N3]2 (3) are formed. The coordination geometry of complex 1 is distorted octahedral with an N4O2 chromophore while complexes 2 and 3 are bromide and azide bridged box dimers respectively with distorted square pyramidal geometry. These complexes showed a axial spectra with g|| > g⊥ ≥ 2.0023. The antibacterial activity and cytotoxicity studies performed showed that these complexes display good activity.

AB - A new NNO donor aroylhydrazone, di-2-pyridyl ketone-3-methoxybenzhydrazone (Hdkm) and three copper(II) complexes of Hdkm have been synthesized and characterized by different physicochemical techniques including single crystal X-ray diffraction technique. The structural analysis of copper(II) complexes revealed that a mononuclear bis coordinated complex [Cu(dkm)2] (1) and two monocoordinated Hdkm with dinuclear metal center [Cu(dkm)Br]2 (2) and [Cu(dkm)N3]2 (3) are formed. The coordination geometry of complex 1 is distorted octahedral with an N4O2 chromophore while complexes 2 and 3 are bromide and azide bridged box dimers respectively with distorted square pyramidal geometry. These complexes showed a axial spectra with g|| > g⊥ ≥ 2.0023. The antibacterial activity and cytotoxicity studies performed showed that these complexes display good activity.

KW - Axial spectra

KW - Box dimer

KW - Copper(II) complex

KW - Distorted square pyramidal

KW - Methoxybenzhydrazone

KW - NO chromophore

UR - https://www.scopus.com/pages/publications/85076101643

U2 - 10.1016/j.ica.2019.119301

DO - 10.1016/j.ica.2019.119301

M3 - Article

SN - 0020-1693

VL - 501

JO - Inorganica Chimica Acta

JF - Inorganica Chimica Acta

M1 - 119301

ER -

Syntheses, spectral aspects and biological studies of bromide and azide bridged box dimer copper(II) complexes of an NNO donor aroylhydrazone

Abstract

Bibliographical note

Other keywords

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