Transtubular bioreactor: A perfusion device for mammalian cell cultivation

Sadettin S. Ozturk; Bernhard O. Palsson; A. Rees Midgley; Craig R. Halberstadt

doi:10.1007/BF01876222

Transtubular bioreactor: A perfusion device for mammalian cell cultivation

Sadettin S. Ozturk, Bernhard O. Palsson, A. Rees Midgley, Craig R. Halberstadt

University of Iceland

University of Iceland

Research output: Contribution to journal › Article › peer-review

Abstract

A transtubular mammalian cell perfusion chamber has been developed that allows separate delivery and control of medium and gas flow to the cells. The hydrodynamic and mass transfer characteristics of the reactor are studied experimentally for both gas and liquid components. Feasibility and potential of the transtubular reactor are demonstrated by the growth of a hybridoma cell line.

Original language	English
Pages (from-to)	55-60
Number of pages	6
Journal	Biotechnology Techniques
Volume	3
Issue number	1
DOIs	https://doi.org/10.1007/BF01876222
Publication status	Published - Jan 1989

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10.1007/BF01876222

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title = "Transtubular bioreactor: A perfusion device for mammalian cell cultivation",

abstract = "A transtubular mammalian cell perfusion chamber has been developed that allows separate delivery and control of medium and gas flow to the cells. The hydrodynamic and mass transfer characteristics of the reactor are studied experimentally for both gas and liquid components. Feasibility and potential of the transtubular reactor are demonstrated by the growth of a hybridoma cell line.",

author = "Ozturk, \{Sadettin S.\} and Palsson, \{Bernhard O.\} and Midgley, \{A. Rees\} and Halberstadt, \{Craig R.\}",

year = "1989",

month = jan,

doi = "10.1007/BF01876222",

language = "English",

volume = "3",

pages = "55--60",

journal = "Biotechnology Techniques",

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T2 - A perfusion device for mammalian cell cultivation

AU - Ozturk, Sadettin S.

AU - Palsson, Bernhard O.

AU - Midgley, A. Rees

AU - Halberstadt, Craig R.

PY - 1989/1

Y1 - 1989/1

N2 - A transtubular mammalian cell perfusion chamber has been developed that allows separate delivery and control of medium and gas flow to the cells. The hydrodynamic and mass transfer characteristics of the reactor are studied experimentally for both gas and liquid components. Feasibility and potential of the transtubular reactor are demonstrated by the growth of a hybridoma cell line.

AB - A transtubular mammalian cell perfusion chamber has been developed that allows separate delivery and control of medium and gas flow to the cells. The hydrodynamic and mass transfer characteristics of the reactor are studied experimentally for both gas and liquid components. Feasibility and potential of the transtubular reactor are demonstrated by the growth of a hybridoma cell line.

UR - https://www.scopus.com/pages/publications/10344232732

U2 - 10.1007/BF01876222

DO - 10.1007/BF01876222

M3 - Article

SN - 0951-208X

VL - 3

SP - 55

EP - 60

JO - Biotechnology Techniques

JF - Biotechnology Techniques

IS - 1

ER -

Transtubular bioreactor: A perfusion device for mammalian cell cultivation

Abstract

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