Stökkva yfir í aðalyfirlit Stökkva yfir í leit Stökkva yfir í aðalefni

Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene

  • C. Szpirer
  • , J. Szpirer
  • , M. Riviere
  • , S. Ingvarsson
  • , B. Vennstrom
  • , M. Q.G. Islam Levan

Rannsóknarafurð: Framlag til fræðitímaritsGreinritrýni

Útdráttur

Using a panel of somatic cell hybrids that segregate rat chromosomes, the localization of five cancer-related rat genes was determined: (i) two thyroid receptor genes, THRA1/ERBA1 and THRB/ERBA2 on chromosomes 10 and 15 respectively, (ii) two ERBB genes, namely the epidermal growth factor gene (EGFR, also called ERBB1) and the ERBB2 gene (also designated neu) on chromosomes 14 and 10 respectively, and (iii) the retinoblastoma gene, RB1, on chromosome 15. The THRA1/ERBA1 and ERBB2/neu genes are thus included in a synteny group, conserved on rat chromosomes 10 and human chromosome arm 17q.

Upprunalegt tungumálEnska
Síður (frá-til)1319-1324
Síðufjöldi6
FræðitímaritOncogene
Bindi6
Númer tölublaðs8
ÚtgáfustaðaÚtgefið - 1991

Fingerprint

Sökktu þér í rannsóknarefni „Chromosomal assignment of five cancer-associated rat genes: Two thyroid hormone receptor (ERBA) genes, two ERBB genes and the retinoblastoma gene“. Saman myndar þetta einstakt fingrafar.

Vitna í þetta